Founders Publications - Kingston Mills

Kingston Mills

Daly, L.M., Johnson, P.A., Nicolson, C., Robertson, J. and Mills, K.H.G. (2005) Innate IL-10 promotes the induction of Th2 responses with plasmid DNA expressing HIV gp120. Vaccine 23, 963-74.

McGuirk, P., Higgins, S., Mills, K.H.G. (2005) Regulatory T cells and the control of respiratory infection. Current Allergy and Asthma Reports. 5 (1): 51-5.

Lipinski, K.S., Pelech, S., Mountain, A., Irvine, A.S., Kraaij, R., Bangma, C.H., Mills, .K.H.G. and Todryk S.M. (2005) Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity. Cancer Immunol Immunother Jun 17: 1-8 [Epub ahead of print]

Boyd, A.P., Ross, P.J., Conroy, H., Mahon, N Lavelle, E.C.and Mills, K.H.G. (2005) Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and enzymatic activity in immunomodulation and cell death. J. Immunol. 175: 730-738.

Noone, C.M. Lewis, E., Frawely, A.B., Newman, R.W., Mahon, B.P., Mills, K.H.G. and Johnson, P.A. (2005) Novel mechanism of immunosuppression by influenza virus haemagglutinin: selective suppression of IL-12p35 transcription in murine bone marrow derived dendritic cells. J. Gen. Virol. 86: 1885-90

Armstrong, M.E., Lavelle, E.C., Loscher, C.E., Lynch, M.A. and Mills, K.H.G. (2005) Induction of proinflammatory responses in the murine hypothalamus following intranasal delivery of cholera toxin: implications for the use of AB toxins as adjuvants in nasal vaccines. J. Infec Dis 192: 1628-33. Epub 2005 Sep 23.

Loscher, CL Leavy, O. Kelleher, D, *Mills, K.H.G and *Roche, H.M. (2005) Conjugated linoleic acid suppresses NFB activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction. J. Immunol 175:4990-4998. (*authors contributed equally).

Lelivelt CL, McCabe MS, Newell CA, Desnoo CB, van Dun KM, Birch-Machin I, Gray JC, Mills KHG, Nugent JM. (2005) Stable Plastid Transformation in Lettuce (Lactuca sativa L.) Plant Mol. Biol. 58, 763-74.

Huo, Z., Sinha, R., McNeela, E.A. Borrow, R., Giemza, R., Cosgrove, C., Heath, P., Mills, K.H.G. Rappuoli, R., Griffin, G.E. and Lewis, D.J.M. (2005) Induction of protective serum meningococcal bactericidal and diphtheria-neutralizing antibodies and mucosal IgA in volunteers by nasal insufflations of Nisseria meningitidis serogroup C polysaccharide-CRM197 conjugate vaccine mixed with chitosan. Infect Immun 73, 8255-65.

Jarnicki, A.G., Lysaght, J, Todryk, S, Mills, K.H.G. (2006) Suppression of antitumor immunity by IL-10 and TGF--producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells. J Immunol (returned for revisions).

Adrian, C., Cullen, S.P., Duriez P.J. Lavelle, E.C., Sutton, C., Sheridan, C., Giesubel, U., Weis, W.E., Mills, K.H.G. and Marin S.J. (2006). Identification of a danger signal cleaved vy Granzyme B an dreleased during natural killer cell induced apoptosis. Immunity (in revision).

Braat, H, McQuirck, P., van Deventer, S.J.H. and Mills, K.H.G. (2006) Prevention of colitis by systemic administration of the pathogen derived imunomodulatory molecule filamentous haemagglutinin of Bordetella pertussis. Gastroenterology (in revision).

Stephenson, I., Nicholson, K.G. Rudin, A. Colegate, A., Podda, A. Bugarini, R., del Giudice, G., Minutello, A., Bonnington, S., Holmgren, J., Mills, K.H.G, and Zambon, M.C. Trivalent nasal inactivated influenza vaccine with non-toxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants: a randomised phase I trial. J. Virol (in review).

Higgins, S. and Mills, K.H.G. TLR-4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-23-driven IL-17. Manuscript in preparation.

Keogh, B., Walsh, K., McGuirk, P., Mills K.H.G. Inducible regulatory T cells suppress pathogenic ThIL-17 cells that mediate autoimmune diseases. Manuscript in preparation.