Founders Publications - Dermot Kelleher

Dermot Kelleher

Dring M, Goulding C, Trimble V, Keegan D, Ryan A, Brophy K, Smyth C, Keeling P, O’Donoghue, D, O’Sullivan M, O’Morain C, Kelleher D*, McManus M* (*joint principal author) The Pregnane X Receptor Locus is Associated with susceptibility to inflammatory bowel disease. Gastroenterology in press (expected Feb 06)

Volkov Y , Long A , Murphy A, Freeley M, Golden-Mason L, O’Farrelly C, Kelleher D The Hepatitis C Envelope 2 protein inhibits LFA-1-transduced Protein Kinase C signalling for T-lymphocyte migration Gastroenterology in press (expected Feb 06)

Eidhin DN, Ryan AW, Doyle RM, Walsh JB, Kelleher D. Sequence and phylogenetic analysis of the gene for surface layer protein, slpA, from 14 PCR ribotypes of Clostridium difficile. J Med Microbiol. 2006 Jan;55(Pt 1):69-83.

El Din El Homasany BS, Volkov Y, Takahashi M, Ono Y, Keryer G, Delouvee A,
Looby E, Long A, Kelleher D. The scaffolding protein CG-NAP/AKAP450 is a critical integrating component of the LFA-1-induced signaling complex in migratory T cells.
J Immunol. 2005 Dec 15;175(12):7811-8.

Abdel-Latif MM, Raouf AA, Sabra K, Kelleher D, Reynolds JV. Vitamin C enhances chemosensitization of esophageal cancer cells in vitro.J Chemother. 2005 Oct;17(5):539-49.

Foran E, McWilliam P, Kelleher D, Croke DT, Long A. The leukocyte protein L-plastin induces proliferation, invasion and loss of E-cadherin expression in colon cancer cells.
Int J Cancer. 2005 Nov 14;

Abdel-Latif MM, Windle HJ, Homasany BS, Sabra K, Kelleher D. Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells. Br J Pharmacol. 2005 Dec;146(8):1139-47.

Brophy K, Ryan AW, Thornton JM, Abuzakouk M, Fitzgerald AP, McLoughlin RM, O’morain C, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R. Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population. Genes Immun. 2006 Jan;7(1):19-26.

Ryan AW, Mapp J, Moyna S, Mattiangeli V, Kelleher D, Bradley DG, McManus R. Levels of interpopulation differentiation among different functional classes of immunologically important genes. Genes Immun. 2005 Oct 13

Papinutto E, Windle HJ, Cendron L, Battistutta R, Kelleher D, Zanotti G. Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter pylori. Biochim Biophys Acta. 2005 Dec 1;1753(2):240-6.

Loscher CE, Draper E, Leavy O, Kelleher D, Mills KH, Roche HM. Conjugated linoleic acid suppresses NF-kappa B activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction. J Immunol. 2005 Oct 15;175(8):4990-8.

Abdel-Latif MM, O’Riordan JM, Ravi N, Kelleher D, Reynolds JV. Activated nuclear factor-kappa B and cytokine profiles in the esophagus parallel tumor regression following neoadjuvant chemoradiotherapy. Dis Esophagus. 2005;18(4):246-52.

Shah SA, Looby E, Volkov Y, Long A, Kelleher D. Ursodeoxycholic acid inhibits translocation of protein kinase C in human colonic cancer cell lines. Eur J Cancer. 2005 Sep;41(14):2160-9.

Duggan SP, Gallagher WM, Fox EJ, Abdel-Latif MM, Reynolds JV, Kelleher D. Low pH induces co-ordinate regulation of gene expression in oesophageal cells. Carcinogenesis. 2006 Feb;27(2):319-327.

Shah SA, Volkov Y, Arfin Q, Abdel-Latif MM, Kelleher D. Ursodeoxycholic acid inhibits interleukin 1 beta [corrected] and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells. Int J Cancer. 2006 Mar 1;118(3):532-9.

O’Toole D, Abdel-Latif MM, Long A, Windle HJ, Murphy AM, Bowie A, O’Neill LA, Weir DG, Kelleher D. Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: a common pathway for epithelial cell injury? J Cell Biochem. 2005 Oct 15;96(3):589-98.

Thews O, Lambert C, Kelleher DK, Biesalski HK, Vaupel P, Frank J. An in vivo tumor model expressing green fluorescent protein for the investigation of metastasis. Int J Oncol. 2005 Sep;27(3):705-12.

Freeley M, Volkov Y, Kelleher D, Long A. Stimulus-induced phosphorylation of PKC theta at the C-terminal hydrophobic-motif in human T lymphocytes. Biochem Biophys Res Commun. 2005 Aug 26;334(2):619-30.

O’Riordan JM, Abdel-latif MM, Ravi N, McNamara D, Byrne PJ, McDonald GS, Keeling PW, Kelleher D, Reynolds JV. Proinflammatory cytokine and nuclear factor kappa-B expression along the
inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus. Am J Gastroenterol. 2005 Jun;100(6):1257-64.

O’Brien JB, McCabe MS, Athie-Morales V, McDonald GS, Ni Eidhin DB, Kelleher DP. Passive immunisation of hamsters against Clostridium difficile infection using antibodies to surface layer proteins. FEMS Microbiol Lett. 2005 May 15;246(2):199-205.

Goulding C, McManus R, Murphy A, MacDonald G, Barrett S, Crowe J, Hegarty J, McKiernan S, Kelleher D. The CCR5-delta32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source. Gut. 2005 Aug;54(8):1157-61. Epub 2005 Apr 29. Erratum in: Gut. 2005 Oct;54(10):1508.

Nugent AP, Roche HM, Noone EJ, Long A, Kelleher DK, Gibney MJ. The effects of conjugated linoleic acid supplementation on immune function in healthy volunteers. Eur J Clin Nutr. 2005 Jun;59(6):742-50.