Opsona Therapeutics – Sending the right signals to the immune system

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Opsona Therapeutics Receives Milestone Payments Under Wyeth Collaboration

15 May 2008

PRESS RELEASE

Opsona Therapeutics Ltd Receives Milestone Payments Under Wyeth Collaboration

Opsona Therapeutics (Dublin, Ireland) has today announced receipt of its first research milestone payments under its agreement from Wyeth Pharmaceuticals, a division of Wyeth (NYSE:WYE).

The collaboration is focused around the role of Toll-Like receptors (TLRs) in inflammation and has been progressing to plan since its inception in January 2006. The companies are working together to identify new compounds for chronic inflammatory diseases, with significant progress being made on the key projects and targets.

Professor Luke O'neill, a founder of Opsona, explains that "Working together with Wyeth, we have identified key tools to aid in a structured drug discovery platform, which has provided an opportunity for Opsona to accelerate its potential field.

About Opsona

Opsona is a drug development company, focused on novel therapeutic and preventative approaches to autoimmune and inflammatory diseases. the company was founded in 2004 as Trinity College campus company, with three of trinity's respected Immunologists. The company is specifically interested in the fielsa od the innate immune system, specifically Toll-Like Receptors (TLR). Opsona has a pipeline of new therapeutics in advanced pre-clinical development which modulate the immune system, including biologics, peptides and small molecules. the company has signed some significant partnering and colllaborative deals, such as Wyeth (USA) and Phylogica (Au).

The company is based at Trinity Centre for Health Sciences at St James' Hospital Dublin 8

www.opsona.com

For further information, please contact:

Dr Mark Heffernan

CEO

+ 353 1 8968499

info@opsona.com



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